Monday, March 16, 2009

Nitrogen Balance & Hormone Manipulation

This article will be different than many training articles you see in the magazines and on the internet. Today I'll cover aspects like hormone manipulation, the importance of a positive nitrogen balance, and proper recovery. Get this and more!

Nitrogen Balance, Hormone Manipulation And Recovery: Critical Factors In Bodybuilding!


Open up any bodybuilding magazine and you usually see a lot of training articles - pretty much the same ones recycled over and over, often listing the champ's routines which are way out of the league of many of us.

Oh, sure, there are some decent "super-features" every so often. But how often do you see an article on aspects like hormone manipulation, the importance of being in a positive nitrogen balance, or proper recovery - these are critical to your bodybuilding success, yet you seldom see quality articles on these topics. This article will cover each of these areas.


Positive Nitrogen Balance

There have been so many articles on protein; I'm not going to squeeze into an already crowded area with yet another article on that topic. What I want to focus on is nitrogen including importance, a bit of history, tips to promote a positive nitrogen balance, and how to stay in a state of positive nitrogen balance.

What is nitrogen and how does it apply to the bodybuilder? According to Tabors Cyclopedic Medical Dictionary, nitrogen is,

"One of the important elements in all proteins,
nitrogen is essential for tissue building."

More important, perhaps, to bodybuilders is that nitrogen is a direct measurement of protein levels in the body.


Does anybody out there remember Weider's nitro test sticks back in the 90's? They were pee strips you used to test your nitrogen balance whenever you wanted - pretty innovative for that time period, don't you think?

For the most part, we are told to eat sufficient protein to maintain a positive nitrogen balance because your body is actually in an anabolic, or building up phase in this state, where a negative nitrogen balance, from lack of adequate protein, indicates a catabolic, or tearing down state.

This is why protein (and eating enough throughout the day) is so important. Lack of adequate protein and your body begins to break down tissue (muscle) to meet its daily protein needs. Our bodies constantly assemble, break down and use proteins (in the form of amino acids, the building blocks of protein). In fact there are literally thousands of different protein combinations used by the body, and each one has a specific function determined by its combination (or amino acid sequence).

I can think back to the 80's and early 90's, and the advice then was to take 3-4 amino acid tablets, and 3-4 liver tablets anywhere from once every hour to once every three hours. Back then, the recommended intake for bodybuilders was much less than what has currently been recommended (1 gram per 2.2 lbs. of body weight), so it's harder now to meet protein needs because the current suggestion is 1 to 1.5 grams per lb. of body weight, at least.

PROTEIN CALCULATOR
Weight 
Results
Old Amount
New Amount

So protein timing/intake becomes critical. Besides taking in high quality protein from food (lean beef, chicken, turkey, fish, eggs), the best way to keep your protein intake at the proper levels are through the use of protein shakes. Whey proteinremains number one, because of its high quality, but milk based proteins are making a comeback, largely because of there longer lasting effects in the body: whey is typically touted as a fast digesting protein, milk as a slow digesting protein.

The other part of getting the most out of your protein intake and thereby maintaining a positive nitrogen balance is carb and fat intake; both are needed in reasonable amounts to insure protein synthesis.

Reasonable amounts of carbs are dependant on goals, for fat loss, stay closer to 80-100 grams a day. For mass, think about 2 grams per lb of body weight. As to fat, I'd stay under 50 grams a day.

CARB CALCULATOR
Weight 
Results
Carbs


Hormonal Manipulation

Hormones are anything that is produced by one organ, carried by the bloodstream to a second, or target organ, and that affects the second organ's function. There are two major classes of hormones: protein hormones and steroid hormones.

  1. Protein hormones are made up of long chains of amino acids and include the following hormones: insulin, glucagon, IGF, all pituitary hormones.

  2. Steroid hormones are derived from cholesterol. They diffuse freely into all cells. However, their "target" cells contain cytoplasmic and/or nuclear proteins that serve as receptors of the hormone. Steroid hormones include testosterone and cortisol.


Hormone Regulation

The levels of hormones circulating in the blood are tightly controlled by three homeostatic mechanisms:

  1. When one hormone stimulates the production of a second, the second suppresses the production of the first.

      Example: The follicle stimulating hormone (FSH) stimulates the release of estrogens from the ovarian follicle. A high level of estrogen, in turn, suppresses the further production of FSH.

  2. Antagonistic pairs of hormones.

      Example: Insulin causes the level of blood sugar (glucose) to drop when it has risen. Glucagon causes it to rise when it has fallen.

  3. Hormone secretion is increased (or decreased) by the same substance whose level is decreased (or increased) by the hormone.

      Example: a rising level of Ca2+ in the blood suppresses the production of the parathyroid hormone (PTH). A low level of Ca2+ stimulates it.


Hormone Transport

Although a few hormones circulating simply dissolved in the blood, most are carried in the blood bound to plasma proteins. For example, all the steroid hormones, being highly hydrophobic, are transported bound to plasma proteins.

The main anabolic hormones in the body are:

 Testosterone:

    This a steroid hormone isolated from the testes. It is produced by the interstitial cells of Leydig (simply, cells in the testes, named after Franz von Leydig, who discovered them). Testosterone performs the following actions in the body: accelerates growth in tissues upon which it acts and stimulates blood flow.

    It stimulates and promotes the growth of secondary sexual characteristics. It's essential for normal growth of the male accessory sex organs, deepens the male voice, and promotes muscular development in men.

 Growth Hormone:

    Human growth hormone (also called somatotropin) is a protein of 191 amino acids. The GH-secreting cells are stimulated to synthesize and release GH by the intermittent arrival of growth hormone releasing hormone (GHRH) from the hypothalamus. GH promotes muscle growth and fat loss, it also promotes growth by binding to receptors on the surface of liver cells - this stimulates them to release insulin-like growth factor-1 (IGF-1; also known as somatomedin).


    This is a protein hormone similar in structure to insulin. It has anabolic effects: Its primary action is mediated by binding to specific IGF receptors present on many cell types in many tissues. The signal is transduced by intracellular events. The effect is the promotion of cell growth and multiplication.

    Almost every cell in the human body is effected by IGF-1, especially cells in muscle, cartilage, bone, liver, kidney, nerves, skin, and lungs. In addition to the insulin-like effects, IGF-1 can also regulate cell growth and development, especially in nerve cells, as well as cellular DNA synthesis.

 Insulin:

    A hormone secreted by the beta cells of the islets of Langerhans of the pancreas. What's the beta cells of the islets of Langerhans? Paul Langerhans was a German pathologist in the 1800's. Islets of Langerhans are clusters of cells in the pancreas, islet means they are detached from surrounding tissues like an island, or, characterized by a difference in structure. Going back to the islets of Langerhans, there are three types of cell clusters: alpha, beta and delta. The beta cells are in greatest abundance and produce insulin.


    Insulin effects many organs. It stimulates skeletal muscle fibers to take up glucose and convert it into glycogen; take up amino acids from the blood and convert them into protein. It acts on liver cells stimulating them to take up glucose from the blood and convert it into glycogen while inhibiting production of the enzymes involved in breaking glycogen back down ("glycogenolysis") and inhibiting "gluconeogenesis"; that is, the conversion of fats and proteins into glucose. It acts on fat (adipose) cells to stimulate the uptake of glucose and the synthesis of fat. It also acts on cells in the hypothalamus.

    In each case, insulin triggers these effects by binding to the insulin receptor—a transmembrane protein embedded in the plasma membrane of the responding cells.


Affects On The Bodybuilder

How does all of this affect the bodybuilder? As many of you know, understanding hormones could take several books and is in fact a field of scientific study. But by having a basic understanding of the main anabolic hormones, realizing the impact they have on muscle growth and by naturally stimulating the production of these anabolic hormones, greater gains can be achieved.

1. Natural Testosterone Production:

    The body's natural production of testosterone can be increased through hard work on the big, compound movements, such as the squatdeadlift andpower clean. Also, the bigger the muscle, the more testosterone is released in response to the exercise. What's bigger than the legs and back, which these exercises primarily target?

    These exercises should be the cornerstones of your routine. Think 5-6 sets of each, heavyweight reps in the 6-10 range. Diet also effects this hormone. Eating a reasonable amount of carbs (no super low carb diet) and some cholesterol is important to maximize release.

    There are several good test boosting supplements on the market, two that come to mind are:

    Fuse

    1. Fuse (Pinnacle)
    2. Novedex XT (Gaspari)

    These are better suited to the older bodybuilder, since natural levels decline as you age - get used to it, everything declines as you age - but young guys can benefit as well.

2. Growth Hormone Production:

    Research shows that when GH is secreted along with testosterone, it magnifies the effect of the testosterone. Research also shows that there is a direct connection between the muscle burn of lactic acid buildup and GH release. What better way to get the burn than through some form of extended sets, like drop sets for example.


    Of course, there are numerous ways to extend a set, but the idea is to train to or past failure on at least some sets. For me, doing one heavy set, after warm-ups, of say, squats, and then going right into a drop set, dropping the weight 3-4 times, until I can barely lift an empty bar, is the ultimate intensity set.

    Another good idea I like is the classic 20 rep squat routine, except I like to use a fairly heavy weight. Still another is to use rest pause, great for those without training partners. Similar to drop sets, this is a great way to extend a set. In fact, as far as hormonal manipulation is concerned, taking a basic exercise done with a heavy weight and a intensity technique like drop sets or rest pause sets offers the best of both worlds - testosterone release and GH release.



3. Insulin Production:

    Insulin being a hormone primarily tied into blood glucose levels, can cause our body to store fat if you have constant spikes all day - that's why watching your simple carb intake is a good idea as eating to many simple carbs in the absence of complex carbs and/or protein causes insulin surges.

    It also causes amino acids and creatine to be stored - this promotes protein synthesis. To get the anabolic actions with out the fat storage, you want to cause an insulin spike at two key times of the day - first thing in the morning when you first wake up and after your work out.

    You do this by drinking a mixture of simple carbs and protein, about 40 grams protein to 40-60 grams carbs.

    You want to get nutrients in the bloodstream as fast as possible after your workout and take advantage of the anabolic actions of insulin at the most critical time; this also starts the recovery and growth process. But in the morning, you are also at a critical time as far as nutrient needs are concerned because you have just come off a short fast while you slept and research shows this creates an anabolic window - take advantage of this by triggering an insulin spike.

    By keeping all of your other meals high in protein and mixed with complex carbs, you can keep insulin spikes under control during the rest of the day.

    One other key is to limit training time to 1 -11/2 hours, any longer and the body will release catabolic hormones, such as cortisol, that can have very destructive, for the bodybuilder, effects.


Recovery

I have often talked about how important recovery is to the growth process. You don't grow by training 6 or 7 days a week using Ronnie Coleman's pre-contest routine, you grow by using a routine compatible with your experience level and by taking enough time between workouts to recover and let growth take place.

How much time? Typically, 5 days of rest before training the same body part again is a good rule of thumb, although for "chemically enhanced" bodybuilders, as little as 2 days may be all that's required, since steroids dramatically enhance the body's recovery ability. Along with this is the fact that individual recovery is based on individual circumstances - age, schedule - both personal and work, type of job, training experience.

An older man with a heavy work schedule and/or personal schedule will not recover as fast as an 18 year old with a light schedule and lots of free time. One of the most misunderstood aspects of training is the fact that you grow in-between workouts when you are recovering, not because of how many workouts you do.

I've said that before, but it bears repeating. Read that sentence about five times because in the 25 years I've been in bodybuilding, I still see far too many people that do not understand the concept of recovery, who think the more you train the faster you grow.


 When Should You Train:

    How recovered you are should determine when you should train. Different muscles recover at different rates than others, and any time you train two or more days in a row, you may be "resting" certain muscles while you train others but you are taxing your entire system, putting a drain on total recovery.

    There are two ways to tell if you have recovered - if the body part you last trained is still sore on your next scheduled training day for that body part, you have not recovered. Rest one more day or until that body part is no longer sore. If you are unusually tired in the morning on any scheduled training day, and you haven't changed anything in your approach, you're probably entering an overtrained state - you aren't allowing enough time for recovery.

    Take off a few days and you'll come back to the gym refreshed with more energy to train. Learn to tailor your workouts to your recovery ability for maximum gains.

Friday, March 6, 2009

Muscle Building Supplementation- What and When


Maximize your muscle-building goals with this detailed and solid supplement program. Both beginner and advanced can gain an edge in their quest for more muscle... Learn what to take and when to build great mass!

Maximum Muscle-Building Supplement Guide: What To Take & When!


You squat, you bench, you curl your way to a better body each and every day you set foot in the gym. Your goals are set, you drive up more weight for more reps.

You are a disciplined hard worker who accepts nothing less than the best from your workouts and nutrition strategies. Sets and reps are counted and documented as well as grams of protein and carbs.

Unfortunately you sometimes find that your gains have slowed or stopped or perhaps even regressed! You need that extra boost. You need a good supplementstrategy to get you on the road to gains once again. But how much and when do you take them?

Supplements
Enlarge Click Image To Enlarge.
You Need A Good Supplement Strategy
To Get You On The Road To Gains.

This guide will lay the foundation for a solid supplement program; one that is detailed and tactfully assembled for maximum benefit. It will be perfectly timed for the greatest results and even spelled out for the beginner to the advanced bodybuilder. So if it is mass that you seek, grow on this!

First let us list and describe the supplements used in this schedule. A thorough explanation is a must regarding timing and dosages. As with all workout and supplement programs, please consult your doctor before beginning.


dotWhey Protein: dot

    As the "Big Man on Campus" of supplements whey is a staple of any supplement program. Easily digested, portable and effective, whey is a must for anyone seeking gains in lean muscle mass. It will serve as a foundation to this supplement program.

    Protein powders in general are great for when you have no time to fix a meal or need extra protein without downing another chicken breast or steak. Whey is a convenient way to feed the muscle and boost gains especially when you need it most.

    Regarding timing and dose whey is most effective when taken as follows (note: most dosages in this article will be for a bodybuilder weighing around 200 pounds):

    20 Grams Upon Waking In The Morning:

      Your body has fasted for up to eight hours or more, so it is imperative that you down a shake first thing when you wake up. This will shut down the catabolic state you may be in and get you on that road to growth once again.

      Now, you want the protein to get in rather quickly so no complexcarbs or fats, just protein, some simple carbs and a few other things (which we will get to in a moment). Your body will thank you for the surge of amino acids!


    20 Grams Pre-Workout:

      It is time to get the levels of aminos in the bloodstream up once again. Taking whey prior to your workout will ensure that your muscles will have a steady stream of protein during your workout so that it can actually begin the rebuilding process early.

    40 Grams Post-Workout:

      This is prime-time to get a quickly digested protein in the body along with about twice the simple carbs (80 grams). No later than 30 minutes after a workout down this cocktail along with a few other ingredients to boost insulin levels which will stimulate protein synthesis by driving glucose and amino acids into the muscle.

arrow View Whey Protein Products Sorted By Top Seller Here.

dotCreatine: dot

    Another well known and effective supplement is creatine. As it gets converted into creatine phosphate in the muscles, which produces energy for contractions during training, supplementing with creatine can ensure that levels of it are topped off. Plus, creatine will force more water into the muscle cells creating an anabolic environment increasing protein synthesis. For strength and size it can't be beat!


    3-5 Grams Pre-Workout:

      Taken with a moderate amount of complex carbs and 20 grams ofwhey protein taking creatine at this time will guarantee your levels are filled up.


    3-5 Grams Post-Workout:

      Within 30 minutes after training combine creatine with 40grams of whey protein and 80 grams of simple carbs to get a potent growth producing shake. After training your muscles are screaming for nutrients so why not give it to them? The insulin response from the simple carbs will also shuttle that creatine right into the muscle.

arrow View Creatine Monohydrate Products Sorted By Top Seller Here.

dotCasein Protein: dot

    Another convenient protein source, casein is slow digesting so it will be digested and released into the bloodstream at a steady rate feeding the muscles over a longer period of time. Whereas whey is used for rapid absorption, casein is used when you need protein to "stick around" a little longer, maybe between meals or for when you know you will not get in another meal for awhile.

    20 Grams Post-Workout:

      Take in 20 grams of casein along with your other post-workout supplements. Whey is used to get instant nourishment to the muscles while casein is taken for when the whey is digested and the muscles still need aminos for recovery. This will also help you stay satiated until you eat your post-workout meal.


    20 Grams In The Middle Of The Night:

      Since it is slow digesting, you can also benefit drinking a shake in the middle of your sleep to ensure your body is getting the protein it needs. During sleep the body is basically fasting and this may cause your body to dip into a catabolic state.

      Ingesting a shake at around three or four hours after going to bed will guarantee your quest for mass is still on track. Now, you may have to set your alarm, but hey, it is all for a good cause.

arrow.

dotGlutamine: dot

    Glutamine is considered a long-term commitment. Though not as noticeably effective as creatine, glutamine has many unseen benefits. As one of the most plentiful amino acids in the body, glutamine assists in recovery by helping muscle cells take up glycogen after a workout, thus supportinggrowth-hormone already in normal healthy ranges and maintaining immune function so you can stay healthy.

    It can also help delay fatigue during a workout so you can turn up the intensity for a longer period of time. The digestive system requires so much glutamine to function that it will take it from muscle tissue so supplementing is a no brainer.

    7-10 Grams Upon Waking In The Morning:

      This will be taken with your small whey shake mentioned above. Again, this will be absorbed quickly to help get your body out of a catabolic state it may have slipped into overnight.


    7-10 Grams Pre-Workout:

      This will help you workout longer and keep up your intensity.

    7-10 Grams Post-Workout:

      Again, taking glutamine after a workout will help with glycogen uptake to quickly start the recovery process and get you in that anabolic state.

    7-10 Grams 30 To 60 Minutes Before Sleep:

      This is another great opportunity to protect your hard earned muscle right before you go to bed. This taken with the small casein shake will help fend off the nightmare of catabolism.

Supplements
Enlarge Click Image To Enlarge.
Take Glutaine Right Before Bed
To Protect Your Hard Earned Muscle.

arrow

dotBranched-Chain Amino Acids: dot

    BCAAs leucine, isoleucine and valine are used for fuel during intense workouts thus preventing your body from scavenging hard-earned muscle for energy. At other times of day BCAAs help stimulate protein synthesis and ward off catabolic hormones.

    5-10 Grams Upon Waking In The Morning:

      BCAAs first thing in the morning is just another weapon in your arsenal to ward off the catabolic effects of fasting most of the night. Your body can readily utilize BCAAs as fuel while whey andglutamine quickly get to muscle tissue.


    5-10 Grams Pre-Workout:

      Again, taking BCAAs before a workout can fuel the body with energy so you can spare muscle tissue and it will also keep you in an anabolic state for growth.

    5-10 Grams Post-Workout:

      This will enhance protein synthesis for greater muscle growth.

arrow 

dotArginine: dot

    Readily converted to Nitric Oxide (NO) in the body arginine is a powerful supplement with a host of benefits. It allows more blood flow to muscle by dilating vessels to allow more nutrients in such as amino acids, glucose as well as a host of hormones. Also, having a greater water delivery into the muscle cells means an increase in protein synthesis, which, in turn, spells more muscle growth.

    2-3 Grams Upon Waking In The Morning:

      At this time arginine will dilate blood vessels to shuttle in the nutrients of other supplements.


    2-3 Grams Pre-Workout:

      This will enhance the natural increase of growth hormone before a workout.

    2-3 Grams 30-60 Minutes Before Sleep:

      This is another time to take advantage of the burst of growth hormone as arginine will only enhance this effect.

arrow 

dotTribulus Terrestris: dot

    Tribulus Terrestris promotes healthy hormone function. It also has the ability to enhance the firing of nerves in muscle for increased strength during workouts. If you need that extra boost in power before a workout Tribulus delivers.


    250-500 Mg Pre-Workout:

      Get that extra surge of testosterone before heading to the gym.

arrow

dotZMA: dot

    ZMA (the combination of zinc magnesium plus vitamin B6) has been shown to support IGF-1 and testosterone levels. Zinc has very powerful recoverybenefits and magnesium will actually calm the nervous system down so the body has an easier time resting. The better you sleep the more opportunity your body has to grow.


    30-60 Minutes Before Sleep:

      30 mg of zinc, 450 mg of magnesium, and 11 mg of B6.

arrow 

dotAntioxidants: dot

    Antioxidants have the ability to rid the body of free radicals which are produced from periods of severe stress such as from an intense workout. It is wise to supplement with vitamins C and E to combat this damage and keep your body in an anabolic state.

    500 Mg Of Vitamin C At Your Post-Workout Whole Meal:

      Vitamin C will support normal joint health and immune function.


    200-400 UI Of Vitamin E At Your Post-Workout Whole Meal:

      Vitamin E supports muscle cell recovery. This antioxidant is also important for skin, nail and hair health.

arrow 

dot
The Schedule For Growth
dot

    Upon Waking In The Morning
    • 20 g whey protein
    • 2-3 g arginine
    • 7-10 g glutamine
    • 5-10 g BCAAs

    Mid-Day Whey

    • 20 g Casein
    • 20 g Protein Shake

    Pre-Workout

    • 20 g whey protein
    • 2-3 g arginine
    • 7-10 g glutamine
    • 3-5 g creatine
    • 5-10 g BCAAs
    • 250-500 mg Tribulus Terrestris

    Post-Workout

    • 40-80 g simple carbs
    • 20 g whey protein
    • 20 g casein protein
    • 7-10 g glutamine
    • 3-5 g creatine
    • 5-10 g BCAAs

    Dinner

    • 500 mg vitamin C
    • 200-400 IU vitamin E

    30-60 Minutes Before Sleep

    • 20 g casein protein
    • 2-3 g arginine
    • 7-10 g glutamine
    • ZMA (30 mg zinc, 450 mg magnesium, 11 mg B6)

    Middle Of The Night

    • 20-30 g casein protein